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Open access Aug 2026

Brain single-cell transcriptome-informed Mendelian randomization identifies potential druggable therapeutic targets for Alzheimer's disease

A brain cell type-resolved genetic prioritization framework for AD is provided, nominating genetically supported candidate druggable targets and linking them to neurodegenerative and immune-related pathways.

Ren-Jun Huang, Li-Qing Guan, Yang Chen et al. · 0 citations