Review
Open access
Sep 2026
MFSD2A in health and disease: lysolipid transport, barrier physiology, and translational boundaries
Major facilitator superfamily domain-containing protein 2A (MFSD2A) is a sodium-dependent lysolipid transporter that delivers lysophosphatidylcholine-bound fatty acids, particularly docosahexaenoic acid, across specialized cellular interfaces. This Review synthesizes structural, biochemical, physiological, genetic, and...
Jin-Heng Gan, Yang Chen, Lin Xin
· Molecular Biomedicine · 0 citations