Author

Yang Gao

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Review Open access Sep 2026

Prostate-specific membrane antigen in malignant brain tumors: vascular heterogeneity, imaging promise, and therapeutic challenges

Clinically, PSMA-targeted imaging shows promise for glioma grading, selected post-treatment assessment, and detection of brain metastases across multiple primary tumors, but therapeutic translation remains limited because compartment-specific target distribution, inconsistent target retention, delivery barriers, and un...

Bihani Pokharel, Ming-Tao Feng, Yue-Fei Yang et al. · Frontiers in Oncology · 0 citations

Open access Jul 2026

Upregulation of macrophage UPP1 promotes lung adenocarcinoma metastasis through an mtROS-cGAS-NLRP3 inflammasome axis.

A macrophage-specific immunometabolic circuit in which UPP1-driven mitochondrial stress activates the mtROS-cGAS-NLRP3 axis, promoting IL-1β-dependent macrophage-tumor crosstalk and metastatic progression is identified.

Mingtao Feng, Chao Gao, Yue-fei Yang et al. · Cell Death Discovery · 0 citations