Bisphenol A aggravates colitis-associated intestinal epithelial injury: Mitochondrial dysfunction and CASP1-associated inflammatory signaling.
OBJECTIVE Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation and epithelial barrier dysfunction. Environmental contaminants may aggravate epithelial injury, but the underlying mechanisms remain unclear. We investigated how bisphenol A (BPA) affects epithelial mitochondrial function and...