One-Pot Synthesis of 1-Pyrrolines via Rh2(esp)2-Catalyzed Intermolecular Reaction of Allylic Azides with Diazomalonates Followed by DBU-Mediated Allylic Imine Cyclization
A one-pot reaction for the synthesis of 1-pyrrolines from allylic azides and diazomalonates has been designed and developed. This conversion involves a sequential two-step process of interception of a diazomalonate by the allylic azide and base-mediated cyclization of the resultant N-allyl imine intermediate. Rh2(esp...