Urinary cell TWIST1 methylation as a non-invasive dual biomarker: A Multicenter study for early detection and recurrence monitoring in bladder cancer.
OBJECTIVE To develop and validate a non-invasive urine-based TWIST1 methylation-specific quantitative methylation‑specific polymerase chain reaction (qMSP) assay for bladder cancer (BC) diagnosis and surveillance to address the clinical need for a reliable complement invasive cystoscopy. METHODS This multicenter stud...