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Yang Zhang

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Open access Sep 2026

Identifying a broad-spectrum influenza inhibitor that blocks multiple functions of viral NS1 protein

Nonstructural protein 1 (NS1) is the key virulence factor of influenza A virus (IAV) that affects the replication and pathogenicity of IAV, which can be used as a promising anti-IAV target. Herein, we identify a marine derived NS1 inhibitor HDN2398 with broad-spectrum anti-IAV effects in different cell lines and female...

Yang Zhang, Ya-Min Luo, Wen-Rui Gai et al. · 0 citations

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