Progression to type 1 diabetes across the autoimmunity and glycaemia continuum: Insights from real-world paediatric and adult cohorts.
BACKGROUND Type 1 diabetes (T1D) follows a staged autoimmune natural history, yet most evidence describing progression derives from highly selected, genetically at-risk cohorts. METHODS Using the TriNetX Network, we identified eight cohorts of autoantibody-positive individuals without prior T1D. Four cohorts had pres...