Integrating plasma-derived circulating proteins with multi-omics approaches to identify potential therapeutic targets for esophageal adenocarcinoma.
Background: Esophageal adenocarcinoma (EAC) is a complex disease often preceded by Barrett's esophagus. Objective: This study aimed to identify potential drug targets and support early prevention and treatment. Method: We integrated cis-protein quantitative trait loci (cis-pQTLs) and genome-wide association study (GWAS...