Author

Yangdi Peng

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Jul 2026

Lactate-associated H3K18 lactylation is involved in IGF2BP2-mediated MARCKSL1 mRNA stabilization and inflammatory signaling in LPS-induced acute lung injury.

The findings decipher a novel H3K18la/IGF2BP2/MARCKSL1 signaling cascade that integrates metabolic reprogramming with m6A epitranscriptomics in ALI, highlighting IGF2BP2 as a promising target for preventive intervention in airway epithelial inflammation.

Yangdi Peng, Jun-Yao Zhang, Yang Yang et al. · Molecular Immunology · 0 citations