Author

Yanruisheng Shao

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#artificial intelligence Preprint Oct 2026

Heuristics are Not Enough: Calibrated and Corrected Caching for Video Diffusion Acceleration

Feature caching has become a mainstream training-free strategy for accelerating video diffusion models by reusing intermediate outputs across denoising steps. However, existing adaptive methods rely on heuristic difference measures misaligned with actual generation quality, employ a single global threshold that ignores...

Ji-Yue Jiang, Zhi-Yu Huo, Yu-Han Chen et al. · 0 citations

Open access Jul 2026

RNA G-quadruplex structure recognition by chimeric peptides

The rational design of chimeric peptides that combine a de novo selected peptide with a native peptide derived from the endogenous DHX36 protein suggests that chimeric peptide design provides a useful strategy for developing selective rG4-targeting ligands and modulating functional nucleic acid structures.

Xi Mou, Jiuming Wang, Yanruisheng Shao et al. · Nucleic Acids Research · 0 citations

Open access Aug 2026

A multimodal representation learning platform for accurate molecular ADMET prediction

Trimole-Hybrid is presented, a task-wise multimodal framework that addresses ADMET heterogeneity by selecting or combining predictors built from complementary molecular representations, and shows sensitivity to changes in essential functional motifs, suggesting its ability to capture ADMET-relevant molecular substructu...

Zhen-Sheng Luo, Dawei Huang, Yanruisheng Shao et al. · bioRxiv · 1 citation