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Author

Yao-Hua Gu

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Sep 2026

Genome-Wide Detection of DNA Lesions at Single-Base Resolution Using Glycosylase-Cleavage Ligation-Assisted Sequencing

Upon exposure to endogenous and exogenous damaging agents, tens of thousands of DNA lesions are generated in the mammalian genome, including uracil (U), 8-oxo-7,8-dihydroguanine (8OG), and apurinic/apyrimidinic (AP) sites. It has been documented that these lesions can impair genomic integrity by inducing single-stran...

Neng-Bin Xie, Tong-Tong Ji, Yong Zhu et al. · 0 citations

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