Open access
2026
Saikosaponin D Ameliorates Non-alcoholic Steatohepatitis by Inhibiting STING-Mediated Macrophage M1 Polarization in Mice.
Saikosaponin D ameliorates NASH by inhibiting the STING-TBK1-IRF3/NF-κB axis in macrophages and promoting M1-to-M2 polarization, identifying SSd as a promising immunomodulatory therapy for NASH.
Wen-Jie Zhang, Yao-Hui Yin, Si-Qi Cheng et al.
· Biological and Pharmaceutica... · 0 citations