AGE-RAGE/NF-κB/SIRT3 signaling cascade is implicated in mitochondrial dysfunction in diabetic gastroparesis
Diabetic gastroparesis is a severe complication of diabetes mellitus, yet its underlying molecular mechanisms remain poorly understood. This study investigated how advanced glycation end products (AGEs) trigger mitochondrial dysfunction through NF-κB activation and SIRT3 suppression in diabetic gastroparesis. We anal...