Yaping Zu

Phosphodiesterase BpdE suppress bacterial proliferation by regulating min operon in Brucella abortus

Brucella spp. are intracellular pathogens utilizing a unique, asymmetric cell cycle to survive within host macrophages. While the biogenesis of the replicative niche is well-studied, the intrinsic regulatory circuits that control the Brucella cell cycle remain incompletely understood. Phosphodiesterase (PDEs) modulates...