Author

Yasmín A. Bertinat

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Open access Sep 2026

Bacterial RNA downregulates MHC-I in tumor cell lines, promoting NK response and delaying tumor growth

Overall, the established model of MHC-I downregulation (either by bacRNA or synthetic hTLR8 agonists) could be used as a therapeutic strategy to promote anti-tumor responses.

A. Serafino, M. Vermeulen, Yasmín A. Bertinat et al. · PLoS ONE · 0 citations