Macrophage-Derived Extracellular Particles Conditioned by Vicenin-2 and Advanced Glycation End-Products Reduce TNF-α-Induced ICAM-1 and VCAM-1 Transcript Expression in Human Endothelial Cells
The contribution of macrophage-mediated inflammation to endothelial dysfunction and atherosclerosis has been recognised for several decades. More recent evidence has implicated cell-derived mediators—extracellular particles and vesicles—as central to the intercellular crosstalk that sustains this inflammatory milieu. E...