Risk assessment of avian influenza A(H5N5) virus from the first human case using the ferret model
The replication kinetics, pathogenesis, and transmission of A/Washington/2148/2025 A(H5N5) virus show that A(H5N5) virus can replicate robustly in mammalian cells and cause severe disease but lacks adaptations supporting efficient airborne spread, informing assessment of the pandemic risk posed by genotype A6 influenza...