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Author

Yasusei Kudo

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Sep 2026

Comparative Transcriptomic and Immune Profiling Reveals a Shared Molecular Identity Between Clear Cell Odontogenic Carcinoma and Hyalinizing Clear Cell Carcinoma.

Clear cell odontogenic carcinoma (CCOC) and hyalinizing clear cell carcinoma (HCCC), rare head-and-neck malignancies with recurrent EWSR1::CREB family fusions, show overlapping morphologic and immunophenotypic features; no standardized systemic therapy for either exists. Given tissue constraints, the molecular relation...

Helen X. Hou, An-Nie Li, Bidish Kumar Patel et al. · 0 citations
Aug 2026

Imbalanced p53–RB signaling triggers cGAS–STING–mediated immune activation in early oral cancer development

Analysis of the TCGA-HNSC cohort showed that combined TP53/CDKN2A alterations significantly separated overall survival and were associated with distinct survival patterns, revealing a previously unrecognized mechanism by which imbalanced p53-RB signaling triggers tumor immunity during the early stages of oral carcinoge...

Zi-Chao Lu, Yasuhiro Mouri, Wenhua Shao et al. · 0 citations

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