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Yasutaka Wakasugi

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Open access Sep 2026

Origin flexibility governs robust ssDNA engagement by the DnaA initiator.

In model bacteria, initiation of chromosome replication requires engagement of single-stranded DNA by oligomers of the DnaA-family initiator assembled within the origin DNA. Although arrays of double-strand motifs recognized by DnaA are a general feature of the origins, the DnaA-binding single-strand elements are eluci...

Nanato Kiyohara, Yasutaka Wakasugi, Kohei Ihara et al. · 0 citations

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