Intratumoral heterogeneity as a potential biomarker for immunotherapy response and postoperative recurrence in NSCLC
Background Intratumoral heterogeneity (ITH) is associated with poor prognosis in various solid tumors. However, its use as a predictive biomarker for immunotherapy in advanced non-small cell lung cancer (NSCLC) is still lacking. Methods We used Maftools to analyze somatic variants of NSCLC from independent cohorts (POP...