Jul 2026
GoMA-DTA: A Gene Ontology-Guided Multimodal Attention Fusion Model for Drug-Target Affinity Prediction.
GoMA-DTA is proposed, a framework integrating gene ontology (GO) functional annotations with protein semantic features with channelwise gating mechanism that uses functional semantics as anchors to dynamically recalibrate ESM-2embeddings, achieving adaptive semantic filtering.
An Xiong, Zheyu Zhou, Yazi Li et al.
· IEEE Transactions on Neural... · 0 citations