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Open access Oct 2026

Astrocyte-derived CXCL14 promotes oligodendrocyte differentiation and remyelination via ERK1/2 signaling: implications for multiple sclerosis therapeutics

Multiple sclerosis (MS) is a debilitating demyelinating disease of the central nervous system (CNS) in which progressive neurological disability is closely linked to the failure of endogenous remyelination. Reactive astrocytes are hallmarks of MS lesions, yet their functional role in myelin repair remains incomplet...

Ye Gong, Hong-Jie Zheng, Rui-Juan Su et al. · 0 citations

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