Open access
Aug 2026
ENHANCED APOPTOSIS VIA AKT/P53 AND CELL CYCLE ARREST VIA CYCLIN MODULATION IN HT-29 CELLS BY BACTEROIDES FRAGILIS SUPERNATANT: A COMPARATIVE STUDY WITH LYSATE
Findings suggest that B. fragilis extracts—especially the supernatant—can induce apoptosis and disrupt cell cycle progression in colorectal cancer cells, highlighting the potential of utilizing bacterial secretomes as the therapeutic potential in cancer treatment.
Yeganeh Marandi Tabar, Mona S. Bagheri, Zahra Shahi et al.
· Journal of Microbiology, Bio... · 0 citations