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Author

Yen-Chung Chen

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Open access Aug 2026

Regulatory logic of neuronal differentiation in the Drosophila visual system

Combinations of terminal selector transcription factors (tsTFs) are thought to establish and maintain the unique identities of the numerous cell types found in nervous systems. However, it remains largely unclear how tsTF combinations are specified during development, and how they then coordinate the type-specific diff...

McKenzie Treese, Yen-Chung Chen, Abigail Tyree et al. · 1 citation
Open access Sep 2026

Temporal regulation of a spatial patterning factor in Drosophila neurogenesis

A central question in neurobiology is how the transient programs that pattern neural progenitors are translated into the enormous, stable diversity of neuronal types. Spatial and temporal cues act only briefly, yet each neuron’s identity is defined and maintained for life by terminal selector transcription factors (TFs...

R. Coyne, Fahad Kamulegeya, C. Lake et al. · 1 citation

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