Author

Yen-Ting Chang

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Open access Sep 2026

Decomposing population differences in type 2 diabetes through a high-resolution GWAS of ~600,000 individuals with East Asian ancestry

Type 2 diabetes (T2D) is a highly heterogeneous metabolic trait, with a higher prevalence in East Asians. Despite extensive genetic studies focusing mainly on Europeans, how genetic risk for T2D is distributed across biological pathways in East Asians in comparison with Europeans remains incompletely understood. Here,...

Kohei Saito, Hsing-Fang Lu, Tatsuhide Inoue et al. · Communications Biology · 0 citations

Open access Jul 2026

Genome-wide association and polygenic risk score analyses of MASLD-related hepatic steatosis severity in a Taiwanese Han population.

BACKGROUND Hepatic steatosis is a highly prevalent metabolic condition and a major contributor to chronic liver disease, particularly in Asian populations. This study was conducted to identify genetic variants associated with the severity of ultrasound-defined hepatic steatosis in a Taiwanese Han population and evaluat...

Ting-Yuan Liu, Jai-Sing Yang, Yu-Chia Chen et al. · Cell & Bioscience · 0 citations