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Yeonjoo Lee

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Review Open access Sep 2026

Rewiring KRAS-driven cancers through the ubiquitin–proteasome system: therapeutic opportunities with a focus on deubiquitinase

KRAS is one of the most frequently mutated oncogenes in human cancers and plays a central role in regulating signaling pathways that control cell proliferation, survival and metabolism. Recent advances in allele-specific inhibitors, particularly those targeting KRASG12C, have demonstrated that direct pharmacological in...

Yeonjoo Lee, Sua Hwang, Hyungkyung Shin et al. · 0 citations

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