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Yessenia Yauri-Huaman

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Open access Oct 2026

MCH-02, a synthetic macamide analog with in vitro FAAH-inhibitory activity, modulates hippocampal endocannabinoid system and BK channel expression without preventing PTZ-induced progressive seizure susceptibility in rats

Epilepsy remains a major neurological disorder, with about 30% of patients showing drug resistance despite the availability of multiple antiseizure medications. The endocannabinoid system (ECS) has emerged as a promising therapeutic target due to its role in regulating neuronal excitability. This study examined the e...

Yessenia Yauri-Huaman, Rodrigo Caceres-Robles, Christell Becerra-Flores et al. · 0 citations

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