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Yi-Chao Wu

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Open access Sep 2026

Trans-Allosteric Activation Releases Distinct Conformational Traps in Kinase Heterodimers

AlloQuant is established, a computational suite that translates AlphaFold3 structural ensembles into quantitative metrics of kinase regulation, including internal network rigidity, metastable-state populations, and sub-angstrom conformational drivers, establishing AlloQuant as a general framework for quantifying how a...

Akira Imamoto, Yi-Chao Wu, Ai Shinobu et al. · 0 citations

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