Author

Yi-Chen Xu

2 papers indexed here

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Open access Oct 2026

Tryptophan metabolism-derived prognostic signature: A potential biomarker for risk stratification and exploratory immunotherapy relevance analysis in prostate cancer.

ObjectiveProstate cancer (PCa) lacks reliable biomarkers to distinguish indolent from aggressive tumors. Tryptophan metabolism (TM) participates in regulating tumor immunity and malignant progression, yet its prognostic relevance in PCa remains poorly characterized.MethodsTranscriptomic and clinical data of TCGA-PRAD c...

An-Ding Gao, Yi-Chen Xu, Ting-Ting Wang et al. · Science in progress · 0 citations

Open access Oct 2026

Glycosaminoglycan-Based CD44-Targeted Nanoparticles for Cancer Therapy: Biological Barriers and Barrier-Informed Design Strategies

Nanoparticle (NP)-based drug delivery has been explored to improve the therapeutic index of anticancer agents by enhancing tumor accumulation and reducing systemic toxicity. Among active targeting approaches, cluster of differentiation 44 (CD44) has attracted attention because of its overexpression in tumor cells and...

Shang-Yu Chen, Sheida Dabiri, Yi-Chen Xu et al. · Nano letters (Print) · 0 citations