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Author

Yi-Chun Miao

1 paper indexed here

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Oct 2026

Discovery of new 7-azaindole derivatives as CSN5 inhibitors with in vitro antitumor activity against triple-negative breast cancer.

COP9 signalosome subunit 5 (CSN5) exerts critical deneddylase activity and is frequently overexpressed in triple-negative breast cancer (TNBC), representing a compelling antitumour target. However, to date, only a limited number of inhibitors targeting CSN5 have been reported, and none of them have advanced into clinic...

Zhi-Wen Yang, Wen-Yi Liu, Yi-Chun Miao et al. · 0 citations

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