Author

Yi-Dan Tang

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Oct 2026

An integrated prediction model using machine learning and dynamics simulation for the selection of transdermal penetration enhancers.

Penetration enhancers (PEs) are widely used in transdermal drug delivery systems (TDDS) due to their cost-effectiveness and excellent biocompatibility. However, the rapid selection of PEs for TDDS is hindered by two critical challenges: first, in vitro permeation tests (IVPT) are costly and time consumption; second, th...

Yi-Dan Tang, Jian-Jia Su, Zheng Wu et al. · Journal of Controlled Releas... · 0 citations

Sep 2026

Dissolving Microneedles Loaded with Lipid Nanoparticles for Co-Delivery of siTNF-α and Dexamethasone as a Dual-Action Therapy for Psoriasis.

Psoriasis, a chronic inflammatory skin disease, presents treatment challenges including systemic side effects and inadequate topical drug delivery. Herein, we developed a hyaluronic acid (HA)-based dissolving microneedle platform delivering tumor necrosis factor-alpha (TNF-α)-targeting small interfering RNA (siRNA) and...

Ya-Xin Cheng, Yun-Feng Han, Xue-Ying Gu et al. · ACS Applied Materials and In... · 1 citation