Open access
Oct 2026
An m7G tRNA-derived fragment mediated thermogenic activation of brown adipose tissue through post-transcriptional repression of Uqcr10.
This study indicates that tRF-Lys-CTT functions as a post-transcriptional regulator of metabolism that suppresses thermogenesis, and provides new insights into the regulatory relationship among the METTL1/m7G/tRF axis and thermogenic control.
Xue-Rui Zhao, Mai-Lin Gan, Xing-Yu Wang et al.
· Journal of Biological Chemis... · 0 citations