Yi Fan

Environmental exposure to semi-volatile organic compounds and COPD progression: Evidence mapping, exposure assessment and metabolomic insights.

Current evidence supports respiratory relevance of several SVOC classes but is insufficient to establish SVOCs as causal drivers of COPD progression, and future longitudinal COPD cohorts should integrate repeated environmental sampling, human biomonitoring, source attribution, mixture modeling and targeted metabolomics to clarify preventable exposure-progression pathways.