Single-cell transcriptomic analysis reveals seed cells and microenvironmental crosstalk in gastric cancer peritoneal metastasis
Peritoneal metastasis is the most frequent and lethal metastatic pattern in gastric cancer, yet the identity of metastatic seed cells and the accompanying microenvironmental remodeling remain poorly defined. Integrated single-cell RNA sequencing analysis of cells derived from primary gastric tumors and peritoneal met...