Author

Yi-Fan Wang

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Sep 2026

DAPK1 overcomes vincristine resistance in osteosarcoma by inhibiting ER-phagy through the ERK signaling pathway.

BACKGROUND The treatment of osteosarcoma still relies on surgery combined with chemotherapy. However, the development of chemotherapy resistance severely weakens treatment efficacy and leads to poor prognosis. Endoplasmic reticulum‑selective autophagy (ER-phagy) can maintain intracellular homeostasis by clearing ER fra...

Pei-Feng Yao, Xin-Yao Cui, Zian Zheng et al. · Tissue & Cell · 0 citations

Aug 2026

RARRES2 deficiency inhibits postmenopausal osteoporosis by promoting ferroptosis-mediated osteoclast differentiation via Nrf2/GPX4 axis inhibition.

RARRES2 knockdown inhibits osteoclast differentiation and alleviates PMOP progression by suppressing the activation of Nrf2/GPX4 and promoting osteoclast ferroptosis.

Yi-Fan Wang, Jia-Bin Lin, Xin-Yao Cui et al. · Connective Tissue Research · 0 citations