Sep 2026
Mycosubtilin suppresses HepG2 proliferation, binds p38α in vitro, and engages ER stress-associated MAPK signaling.
Findings identify p38α as a direct in vitro binding target of Myco and support Myco as a candidate for further evaluation in additional HCC models, where JNK1 engagement remains computationally predicted.
Jun Yang, Qian Zhou, Xi-Yuan Cao et al.
· Bioorganic chemistry (Print) · 0 citations