Bayesian flow networks (BFNs) jointly model atomic coordinates and atom types for structure-based drug design, but their generative dynamics remain poorly understood. We show that the two channels resolve on different terms: atom types pass through a sharp commitment transition at tc1, whereas coordinate precision im...
Liang-Ji Zhou, Yuan-Qiu Chen, Tong-Tong Chen et al.· Journal of Chemical Informat...· 0 citations
The proband has harbored a complex balanced translocation involving four non-homologous chromosomes in a Chinese pedigree using optical genomic mapping (OGM), which has demonstrated certain advantages in characterization of complex chromosomal structural abnormalities.
Yi-Juan Huang, Yuan-Qiu Chen, Shao-Bin Lin et al.· Zhonghua yi xue yi chuan xue...· 0 citations
The compound heterozygous IBA57 mutations c.310G>T and c.826C>T lead to reduced IBA57 protein expression, selective impairment of respiratory chain complex II, and transcriptional dysregulation of the PI3K-Akt pathway, together contributing to the MMDS3 phenotype in the proband and the affected fetus.
Yi-Juan Huang, Chen-Yu Gou, Yuan-Qiu Chen et al.· Frontiers in Genetics· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.