Yi-Jun Ge

CCR5 protects against permanent brain ischemia by suppressing neuronal ferroptosis through AMPK/ACC signaling

Ischemic stroke triggers devastating neuronal injury cascades, and ferroptosis acts as a key mediator of post-ischemic neuronal loss. Although C–C chemokine receptor type 5 (CCR5) has been traditionally implicated in post-stroke neuroinflammation, its cell-specific role in neuronal ferroptosis remains obscure. Here, we...