Author

Yi-Jun He

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Open access Aug 2026

MYDGF as a telomerase activator and therapeutic target for osteoarthritis

Osteoarthritis (OA) involves progressive cartilage breakdown. This is driven by impaired chondrocyte function and an imbalance in the extracellular matrix homeostasis. However, the key upstream regulators that maintain healthy chondrocytes are still not fully known. Here, we report that myeloid-derived growth factor (M...

Yi-Jun He, Chu-Jun Li, Ke-Xin Chen et al. · Advanced Biotechnology · 0 citations

Review Open access 2026

RAD51 in homologous recombination-mediated DNA damage repair and genome stability: Mechanisms, regulation and implications for disease

Homologous recombination (HR) is a high-fidelity DNA repair pathway that preserves genome stability through the accurate repair of DNA double-strand breaks. RAD51 is the central recombinase of HR and catalyzes the key processes of homology search and strand invasion through the formation of nucleoprotein filaments on s...

Tao Zhou, Yilin Cui, Xinxin Liang et al. · Ageing and Cancer Research &... · 0 citations