Sarcopenia is a disease characterized by reduced muscle mass and strength. In recent years, increasing evidence suggests that gut microbiota (GM) may play an important role in the pathogenesis of sarcopenia. GM is associated with muscle health by affecting muscle metabolism, regulating inflammatory responses, and promo...
Yi-Kai Liu, Shuai Lu, Lei Li et al.· Frontiers in Nutrition· 1 citation
This sc-eQTL MR study reveals immune cell-specific causal regulatory networks in PCOS, where GLIPR1 in non-classical monocytes represents a high-confidence protective target, while XBP1 provides suggestive evidence for immune-mediated pathogenesis.
Jia-Huan Zhang, Yi-Kai Liu, Dan-Hong Lin et al.· Science in progress· 0 citations
Purpose of review This review aims to summarize recent advances in the mechanistic understanding of senile osteoporosis, with particular focus on the interconnected roles of cellular senescence, metabolic dysfunction, and systemic homeostatic imbalance in age-related skeletal degeneration. Recent findings Emerging evid...
Ruifeng Bai, Zi-Shuai Huang, Xuan Tian et al.· Frontiers in Aging· 0 citations
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