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Author

Yi-Lin Chen

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Review Open access Oct 2026

Optimizing antibody-dependent cellular phagocytosis for cancer immunotherapy: mechanisms, constraints, and therapeutic strategies.

BACKGROUND Accumulating evidence demonstrates that antibody-dependent cellular phagocytosis (ADCP), mediated by tumor-associated macrophages via Fcγ receptors (FcγR), represents a key Fc-dependent effector mechanism for selected antitumor monoclonal antibodies, including rituximab in B-cell malignancies, trastuzumab in...

Ming-Yi Ju, Miao Zhang, Shuai Ma et al. · 0 citations

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