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Open access Sep 2026

Development and validation of a multiplex TaqMan real-time quantitative PCR assay for the simultaneous detection of six major bacterial respiratory pathogens in goats

Background Respiratory disease caused by bacterial and mycoplasmal pathogens is an important threat to goat health, and mixed infections complicate etiological diagnosis. Rapid multiplex detection is therefore valuable for clinical investigation and surveillance. Methods Two triplex TaqMan real-time quantitative PCR (q...

M. Fu, Yi Liu, Ze-Yang Zhang et al. · 0 citations
Open access Sep 2026

Endoplasmic reticulum stress activated by IBRV induces mitophagy to impair the RIG-I-MAVS-mediated type I interferon pathway and facilitate viral replication.

Infectious bovine rhinotracheitis (IBR) is a globally recognized infectious disease. The causative agent infects the respiratory and reproductive tracts of cattle, resulting in substantial economic losses to the cattle industry. Endoplasmic reticulum stress (ERS) and mitophagy play critical roles in maintaining cellula...

Shi-Fan Li, Yi-Na Zhao, Rong Mo et al. · 0 citations

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