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Author

Yi-Mao Wu

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Review Open access 2026

Decoding the Immuno-Oncology-Microbiome axis: Breakthroughs in mechanisms, technologies, and clinical applications

The Immuno-Oncology-Microbiome (IOM) axis is a tripartite regulatory system involving microbiota, immune cells, and tumors, which critically modulates cancer progression and therapy response. This systematic review synthesizes key advances from 2022 to 2025, illustrating the field’s evolution from macro-associations to...

Yi-Mao Wu, Fei-Yang Tang, G. Zengin et al. · 0 citations
Review Aug 2026

Logic-gated nanoregulators: A paradigm shift from drug delivery to pre-programmed multi-target immunotherapy.

This review traces the evolution of nanomedicine from a passive drug delivery vehicle to a therapeutic program encoded in a physical structure, and examines the design constraints that will determine whether the next generation of cancer nanomedicines fulfills its clinical promise.

Yi-Mao Wu, Fei-Yang Tang, Junying Lee et al. · 0 citations
Review Open access Jul 2026

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including c...

Yi-Mao Wu, Xiao-Yan Chen, Zi-Chang Chen et al. · 0 citations

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