Author

Yi-Ming Zhong

3 papers indexed here

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Open access Oct 2026

Genomic epidemiology reveals niche specialization and a virulence-resistance trade-off in ST23 and ST11 hypervirulent Klebsiella pneumoniae.

ST23 retains a classic hypervirulent phenotype, whereas ST11 represents a hospital-adapted convergent clone characterized by a complex resistome, an incomplete canonical virulence repertoire, and separate plasmid systems, suggesting that convergence in ST11 involves coexisting distinct plasmid systems rather than detec...

Fang Yang, Qin-Rui Lai, Wen-En Liu et al. · International Journal of Inf... · 0 citations

Oct 2026

LNA Blocker-Enhanced Multiplex Chip-Based Digital PCR for Ultrasensitive Quantification of Liver-Specific DNA Methylation in Plasma

Sensitive and selective quantification of rare methylated DNA in plasma remains a major analytical challenge. For methylation targets located in CpG-sparse regions, bisulfite conversion produces only subtle sequence differences between methylated and unmethylated alleles, thereby hindering selective amplification. He...

Yan-Ping Lan, Xin Yang, Tian-Bin Chen et al. · Analytical Chemistry · 0 citations

Open access Sep 2026

Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent Klebsiella pneumoniae Infection

Hypervirulent Klebsiella pneumoniae (hvKP) causes invasive infections, including bloodstream infections and liver abscesses, and dysregulated host inflammation may exacerbate liver injury. We investigated whether pretreatment with Humanin, a mitochondria-derived anti-inflammatory peptide, could attenuate hvKP-associate...

Yi-Ming Zhong, Dina Haishaer, Wei-Dong Cai et al. · Pathogens · 0 citations