Open access
Oct 2026
Propionate promotes CD8+ T-cell infiltration and enhances immunotherapy efficacy in colorectal cancer
Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota are increasingly recognized as regulators of host immunity, yet the role of individual SCFAs in shaping the tumor immune microenvironment in colorectal cancer (CRC) remains poorly defined. This study aims to investigate the role of propi...
Jing-Ying Pan, Le Tong, R. Fei et al.
· Journal for ImmunoTherapy of... · 0 citations