A pH-responsive and self-healing CEC/PEG-(CHO)2 hydrogel for controlled neuropeptide S delivery and endogenous neural repair after spinal cord injury
A pH-responsive CEC/PEG-(CHO)2 hydrogel scaffold was engineered for local delivery of neuropeptide S (NPS) to modulate the hostile microenvironment after spinal cord injury (SCI). The scaffold exhibited accelerated degradation under acidic conditions mimicking the injured site, enabling controlled release of NPS. Its p...