Sep 2026
BACKGROUND
Direct reprogramming of cardiac fibroblasts (CFs) into induced cardiomyocytes (iCMs) holds promise as a therapeutic strategy for heart regeneration. After myocardial infarction (MI), resident quiescent CFs (QCFs) activate and differentiate into myofibroblasts (MFs) in the infarcted region that drive patholog...
Jing-Dong Wu, Chun Yang, Dong Wu et al.
· Circulation · 0 citations
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Open access
Sep 2026
Alzheimer’s disease (AD) is characterized by amyloid-
β
(Aβ) deposition, tau pathology, synaptic injury, neuroinflammation, oxidative stress, and disrupted organellar homeostasis. Peroxisomes maintain lipid and redox balance through very-long-chain fatty acid (VLCFA)
β
-oxidation, plasmalogen biosynthesis, and re...
Tao Liu, Yi-Ran Liu, Yi-Chi Zhang et al.
· Frontiers in Aging Neuroscie... · 0 citations
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