Yi-Ru Chen

Ganoderic Acids Alleviate Dexamethasone-Induced Muscle Atrophy Potentially via Regulating Protein Synthesis/Degradation, Attenuating Oxidative Stress, and Antagonizing Glucocorticoid Receptor.

Ganoderic acids (GA), a class of specific triterpenoids found exclusively in Ganoderma lucidum, have broad pharmacological activities. The purpose of this study was to determine whether GA attenuates dexamethasone (DEX)-induced muscle atrophy and to explore the underlying mechanisms. The therapeutic effect of GA (at in...