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Review Open access Aug 2026

Circulating tumor DNA in neoadjuvant therapy for solid tumors

Circulating tumor DNA (ctDNA), a core component of liquid biopsy, demonstrates significant potential in the field of neoadjuvant therapy for solid tumors. This review systematically examines the role of ctDNA across the pre-, intra-, and post-neoadjuvant treatment phases, with a focus on its value in predicting therape...

Xue-Qin Huang, Yuan-He Deng, Yi Shen · 0 citations
Review Open access Aug 2026

Decoding the molecular mechanisms of pyroptosis and its therapeutic development prospects

Pyroptosis is an emerging form of inflammatory programmed cell death primarily mediated by the gasdermin protein family, characterized by cell swelling, membrane pore formation, and the release of pro-inflammatory cytokines such as IL-1β and IL-18. This mode of cell death has garnered significant attention due to its c...

Yi Shen, Qiang-Qiang Zheng, Yang Yuan et al. · 0 citations

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